COA
| Appearance | White to off white powder | Consistent |
| Purity(HPLC) | ≥98% | 99% |
| Water | <6.0% | 5.43% |
| Acetic Acid | 3.0-8.0% | 6.45% |
| Trifluoroacetic Acid | <0.25% | 0.08% |
| Peptide | ≥80% | 88.45% |
| MS | Consistent | Consistent |
Description
Application
ACE-031 is a fusion protein that is soluble and is known to have a positive feedback mechanism in the increasing muscle strength and mass. The polypeptide is under research for the treatment of various condition and diseases such as metabolic diseases, cardiovascular anomalies, renal neoplasms during childhood, cancer, age related muscle loss and other neuromuscular diseases. ACE-031 is biopeptide that has therapeutic properties that are mainly based on the activin receptor type 2 or ActRIIB. The polypeptide inhibits cell signaling by blocking ActRIIB receptor thereby increasing muscle strength and mass. It is an artificially synthesized polypeptide of the natural antibody and a part of the ActRIIB receptor. When recombinant technology is used to fuse the proteins, it eliminates myostatin and other biomolecules that limit muscle growth and strength. ACE-031 is classified under the category of proteins in the TGF-beta super family, which are essential in the regulation of muscle growth and strength. ACE-031 mechanism of action is through the switching on and up regulation of the muscle growth process, experimental studies reveal that the polypeptide acts by inhibiting the ActRIIB receptor and promotes myoblasts differentiation, development, and maturity. According to studies administration of ACE-031 for 2 weeks increases skeletal muscle density, increases adiponectin levels and reduces leptin level in the system. The polypeptide is composed of 368 amino acids in the sequence; this makes a very large and complex polypeptide. Muscle growth is mainly accentuated by the production of muscle cells and this occurs via the amino acids and other essential components. TGF beta protein super family, which is the main regulator in the switching on and off the muscle development through the amino acids. When the ActRIIB receptors interact with GDF-8, it causes a signal transduction which in causes the initiation of myoblasts differentiation, development and maturity. ACE-031 is a protein under research for enhancing muscle cell differentiation in a recombinant fusion is vital in inhibiting factors that limit muscle growth and generation of myoblasts by endogenous binding to the cells. The blockage of the antagonist causes an enhanced production of myoblasts, muscle function and improved muscle strength. The mechanism can prove to be essential in dealing with problems such as muscular dystrophy, androgen deprivation, and muscle loss associated with corticosteroids among other conditions. Unlike the generation of mutation specific ribonucleotide based therapy, the clinical development for Duchene muscular dystrophy or what is commonly called DMD, ACE-031 can be very beneficial because it is not affected by existing mutations.Effects
Follistatin-344 significantly increases muscle growth and muscle strength (by blocking the Moystatin activity) - it promotes hyperplasia (growth of new muscle cells) as well as active hypertrophy (increase in cell size). Follistatin-344 exhibits a potent anabolic activity (yet without concomitant androgenic activity). Taking Follistatin-344 results in muscular hyperplasia (growth of new muscle fibres) and active hypertrophy (increase in size of existing muscle fibres) Follistatin-344 has a strong ability to keep sportsmen in shape and maintain their muscle mass even when they stopped exercising Follistatin-344 significantly increases performance Follistatin-344 exhibits a potent anti-aging effect, with a significant impact on rejuvenation of all body tissues Follistatin-344 promotes body´s fat burning Follistatin 344 / FST promote muscle growth due to the unique mechanism of action, FST joint use of steroids, IGF has better results. It only acts on muscle tissue , after use will not cause the proliferation of other tissue cells. Follistatin 344 / FST works by binding to and inhibiting transforming growth factor-β (TGF-β) peptides such as myostatin which is responsible for regulating and limiting muscle growth.Storage
Follistatin 344 Lyophilized Follistatin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FST should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.Other Products
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Contact Us
Hjtc (Xiamen) Industry Co., Ltd.
Xiamen Huayongjian Biotechnology Co., Ltd.
Contacts: June & Eason
Whatsapp:+8618206063252; +8618759200098
E-mail: [email protected];
Web site:https://www.steroidpowder-hjtc.com/ http://www.safeststeroid.com/ http://www.glassviallabels.com/ https://hjtc-printing.en.made-in-china.com/
