The recommended dosing of Follistatin-344
Follistatin-344 should be taken in a dose of 100 to 200 mcg once per day, for the period of 10-20 days.Precautions: Follistatin-344 is not intended for use by women.Abstract
Follistatin 344 is a performance enhancer that has been recently gaining a lot of popularity. Simply put it is a protein. It is high in non-essential amino acid cysteine, but with attached carbohydrates. Its function is to bind and inhibit myostatin and other transforming growth factor peptides. These peptides prevent the body from putting on additional muscle fast. Suppress transforming growth factor peptides and you get a body that can put up an impressive amount of muscle, really fast. It’s no wonder that Follistatin 344 is gaining such a following in the bodybuilding circles. In recent times, bodybuilding and working out has gained a lot of popularity. With an acceptance in the mainstream, also comes a demand for performance enhancers and substances that will help you achieve the result that you desire. However, the fact that bodybuilding is an exact science is not very well known and performance enhancers are still looked at with suspicion. To put it simply, Myostatin inhibitors lower or completely stop the production of myostatin in your body. Pretty obvious right? Myostatin is a protein encoded by the MTSN gene. It is a growth differentiation factor and to put it simply, limits the amount of muscle one can build. It also places limits on how FAST you can build muscle. Without it, we could be gain upwards of 1 or 2lbs of muscle DAILY.Application
Follistatin-344 significantly increases growth and strength of muscles by blocking Myostatin (GDF-8 - a protein inhibiting muscle growth). Follistatin-344 seems to be a very promising Myostatin inhibitor, possessing a sufficient safety profile. Follistatin-344 is also a perfect choice for those sportsmen who cannot exercise on a regular basis any longer or for those who stopped exercising, but they still want to stay in shape, having a huge muscle mass. It has been proved, that the less strenuous muscle load and the less physical activity is, the higher concentration of Myostatin is reached. Follistatin-344 (also known as activin-binding protein) is an autocrine glycoprotein encoded by the FST gene that is expressed in nearly all tissues. Its primary function in the body is bioneutralization of members of the TGF-β superfamily, with a particular focus on activin and paracrine hormones. Follistatin is a potent Moystatin inhibitor. An original Follistatin acted also as an activin inhibitor, which on the other hand stimulates the secretion of follicle-stimulating hormone - FSH (activin regulates the growth and differentiation of all cell types, including cells within sexual glands, pituitary gland and skeletal muscles). Therefore, scientists developed a particular Follistatin (Follisttain-344) that is derived from the original one and that is capable of blocking preferentially Moystatin activity.Commerce Clause
Follistatin is recommended for research, but people who have tried it themselves typically take injection 100 mcg/day of dose via injections for 10 to 30 days. Ideally, it can be taken every third day. People who have taken doses up to 200 mcg have not shown suffered from any adverse effects than the ones who have taken lower doses.Contact Us
Hjtc (Xiamen) Industry Co., Ltd.
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Description
Follistatin also known as activin-binding protein is a protein that in humans is encoded by the FST gene. Follistatin is an autocrine glycoprotein that is expressed in nearly all tissues of higher animals.Its primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone. Follistatin is naturally found in the skeletal muscle of almost all mammals with advanced or developed characteristics, such as humans, rodents, and cows. Follistatin is high in the non-essential amino acid cystine but unlike most proteins discussed in the fitness world, follistatin has carbohydrates attached to it. Follistatin works by binding to and inhibiting transforming growth -β (TGF-β) peptides such as myostatin which is responsible for regulating and limiting muscle growth. It's also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow. ACE-031 is a soluble fusion protein that has been shown to increase muscle mass and strength in research studies. ACE-031 is being studied as a treatment for metabolic diseases, renal neoplasms of childhood, cardiovascular anomalies, age-related muscle loss, and cancer treatment related muscle loss and neuromuscular diseases. ACE-031 is a biologic therapeutic, based on activin receptor type IIB (ActRIIB). The molecule inhibits signaling via the ActRIIB receptor binding and increase muscle mass and strength. ACE-031 is a recombinant fusion protein that is artificially synthesized by fusion of standard antibody and a portion of ActRIIB receptor. The recombinant fusion protein eliminates myostatin and other biomolecules that limit muscle strength or growth. Follistatin 344 / FST was initially identified as a follicle-stimulating hormone inhibiting substance found in ovarian follicular fluid. FST is a high-affinity activin binding protein that can act as an activin antagonist. Two alternatively spliced follistatin mRNAs exist, encoding mature FS with 288 amino acid residues (FS-288) and 315 aa residues (FS-315). Natural FS purified from porcine ovaries is primarily a carboxy-terminal truncated form of FS-315 composed of 300 aa residues. Follistatin 344 / FST quickly gained popularity in the bodybuilding community as a potential supplement to rapidly increase lean tissue mass. Another protein, follistatin-related gene acts on similar pathways as FST regarding its muscle building properties. Increased lean tissue mass could give a bodybuilder an advantage in a competitive setting. FST is a single chain gonadal protein that specifically inhibits follicle stimulating hormone release. The single FST gene encodes two isoforms Follistatin 317 and Follistatin 344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. There is evidence linking polycystic ovary syndrome and follistatin. Follistatin binds directly to activin and functions as an activin antagonist. It specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone. Subunit : Monomer Subcellular Location : Secreted. Tissue Specificity : Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid. Effects of Follistatin
Follistatin-344 significantly increases muscle growth and muscle strength (by blocking the Moystatin activity) - it promotes hyperplasia (growth of new muscle cells) as well as active hypertrophy (increase in cell size).Follistatin-344 exhibits a potent anabolic activity (yet without concomitant androgenic activity). Taking Follistatin-344 results in muscular hyperplasia (growth of new muscle fibres) and active hypertrophy (increase in size of existing muscle fibres)Follistatin-344 has a strong ability to keep sportsmen in shape and maintain their muscle mass even when they stopped exercising. Follistatin-344 significantly increases performance Follistatin-344 exhibits a potent anti-aging effect, with a significant impact on rejuvenation of all body tissues. Follistatin-344 promotes body´s fat burning.Dosage
Follistatin is recommended for research, but people who have tried it themselves typically take injection 100 mcg/day of dose via injections for 10 to 30 days. Ideally, it can be taken every third day. People who have taken doses up to 200 mcg have not shown suffered from any adverse effects than the ones who have taken lower doses.
Packaging&Shipping
1. By Express
------Suitable for under 50kg, Fast:3-7 days. High cost; Door to door service. Easy to pick up the goods. 2. By Air ------Suitable for more than 50 kg, Fast:3-7 days, High cost, airport to airport. professional broker needed. 3. By sea ------Suitable for more than 500kg. Slow: 5-45 days, Low cost. Port to Port, professional broker needed.
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