SARM SR9011 Pharmaceutical Raw Powder for Boosting Exercise Endurance CAS 1379686-30-2

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  • SARM SR9011 Pharmaceutical Raw Powder for Boosting Exercise Endurance CAS 1379686-30-2
  • SARM SR9011 Pharmaceutical Raw Powder for Boosting Exercise Endurance CAS 1379686-30-2
  • SARM SR9011 Pharmaceutical Raw Powder for Boosting Exercise Endurance CAS 1379686-30-2

PRODUCTS DETAILS

SR9011 Quick Details

Cas No 1379686-29-9 Synonyms 3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine- 1-carboxamide Formula C23H31ClN4O3S Molucelar weight 479.03524

SR9011 Description

SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal  substrates.   SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols.  Usage levels of 5% to 10% by weight are recommended.   SR9011 is a potent and specific synthetic REV-ERB. It also has good in vivo plasma/brain exposure.  The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression  of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters  circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice.  The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and  adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced  obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.

How to Use SR9011?

In vitro: SR9011 was used at 5-10 μM concentration in vitro and in cellular assays. In vivo: IP administration of SR9011 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models.

Competitive Advantages

1. All powders are factory directly supplying. 2. Our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries. 3. Our products are of high quality at competitive prices. Free samples are available. 4. Well discreet packing. Fast and secure delivery by DHL, TNT, FedEx, HKEMS, UPS, etc. 5. Flexible and Untraceable payment terms. 6. Exclusive customer service and 24/7 online timely and helpful after-sale service.

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FAQ

1,Can i get some samples? Yes, we can supply the free sample, but the shipping cost be paid by customer 2,How to confirm the Product Quality before placing orders? We offer free sample,After you test the sample,you can know our quality.then place order. 3,Can you guarantee I can get my goods without any custom problem? Yes, We have Reship Service.You can get your goods without any problem. 4,When you ship my order? Normally within 2 to 3 days after confirming your payment 5,How about the quality guarantee period? 24 Months 6,How do you hide the products?. Our shipping worker is very professional.They can pack various professional discreet package for hidding the products.

Contact Us

Hjtc (Xiamen) Industry Co., Ltd.

Xiamen Huayongjian Biotechnology Co., Ltd.

Contacts: June & Eason Whatsapp:+8618206063252; +8618759200098 E-mail:  [email protected]

          [email protected] Web site:https://www.steroidpowder-hjtc.com/                 http://www.safeststeroid.com/                 http://www.glassviallabels.com/                 https://hjtc-printing.en.made-in-china.com/

Order Guide

how to make order

step1

Pre-sale service

1.As for your every inquiries, we always reply timely and patiently. All of the relevant information will be provided to help you to make a wise choice

2. if you need we can offer provide you with COA , Cook Recipes Of Steroid Oil , Feedback Of Other Customers

Step2

payment

1.we'd like to accept bank transfer, Western Union , Moneygram , Bitcoin

Step3

delivery

2.we are support Transportation: DHL, UPS, TNT, EMS, Hongkong EMS, FedEx or Other

3.After confirming your payment, shipping arrangement and package pictures will be provided within 24 Hours ; Tracking number will be provided within 72 Hours.

4.For important parcel information, such as: Left Original Country , Arrived At Destination Country , Passed Customs , Out For Delivery , Delivered, those information will be sent to you timely.

Step4

After-sales service

1.you could consult us for any questions, we offer 7*24h good servies and Tech-support.

 

Packaging & Delivery

1. By Express 

------Suitable for under 50kg, Fast:3-7 days. High cost; Door to door service. Easy to pick up the goods.

2. By Air  ------Suitable for more than 50 kg, Fast:3-7 days, High cost, airport to airport. professional broker needed. 3. By sea ------Suitable for more than 500kg. Slow: 5-45 days, Low cost. Port to Port, professional broker needed.

After Sales Service

1.Quality steroid powder and Favorable pricesFavorable prices 2.Newest and updated discreet ways 3.The most professional express 4.One to one Exclusive customer service 5.Flexible and Untraceable payment terms 6.24/7 online helpful After-sale service 

Synthesis of SR9009 and SR9011

Compounds were synthesized by reductive amination of 5-nitro-2-thiophenecarboxaldehyde with 4-chlorobenzylamine and sodium triacetoxyborohydride yielded the secondary amine. A second reductive amination with 1-Boc-pyrrolidine-3-carboxaldehyde yielded the tertiary amine. This compound was treated with trifluoroacetic acid to remove the Boc-protecting group, and then reacted with either ethyl chloroformate (SR9009) or pentyl isocyanate (SR9011) to give the desired products.

SR9011 COA

Item Specification Result
Appearance An odorless, almost white or white powder pass
Identificaton The retention time of the major peak is confirm to the RS pass
Loss on Drying Not more than 0.5% 0.33%
Assay(HPLC) Not less than 99.0% 99.59%
Ignition residue Not more than 0.1% pass
Heavy metal Not more than 20 ppm pass
 
 

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