Letrozle(Femara) 2.5mg Quick details
| Product Name | Letrozole |
| Alias | Femara |
| CAS | 112809-51-5 |
| Purity | 99% |
| Packing | foil bag or tin. |
| Appearance | White or light yellow crystal |
| Standard | Enterprise Standard |
| Storage | Shading , confined preservation |
| Usage | Anti-estrogen |
| Molecular Fomular | C17H11N5 |
| Molecular Weight | 285.31 |
| Molecular Structure | |
Letrozle(Femara) 2.5mg Description
Letrozole is approved by the United States Food and Drug Administration (FDA) for the treatment of local or metastatic breast cancer that is hormone receptor positive or has an unknown receptor status in postmenopausal women. Letrozole has been used for ovarian stimulation by fertility doctors since 2001 because it has fewer side-effects than clomiphene (Clomid) and less chance of multiple gestation.he risk of birth defects. A more detailed ovulation induction follow-up study found that letrozole, compared with a control group of clomiphene, had significantly lower congenital malformations and chromosomal abnormalities at an overall rate of 2.4% (1.2% major malformations) compared with clomiphene 4.8% (3.0% major malformations). Despite this, India banned the usage of letrozole in 2011, citing potential risks to infants.
Letrozle(Femara) 2.5mg Applications
Letrozole has been used for ovarian stimulation by fertility doctors since 2001 because it has fewer side-effects than clomiphene (Clomid) and less chance of multiple gestation. A Canadian study presented at the American Society of Reproductive Medicine 2005 Conference suggested that letrozole may increase the risk of birth defects.[citation needed] A more detailed ovulation induction follow-up study found that letrozole, compared with a control group of clomiphene, had significantly lower congenital malformations and chromosomal abnormalities at an overall rate of 2.4% (1.2% major malformations) compared with clomiphene 4.8% (3.0% major malformations). Despite this, India banned the usage of letrozole in 2011, citing potential risks to infants.In 2012, an Indian parliamentary committee said that the drug controller office colluded with letrozole's makers to approve the drug for infertility in India and also stated that letrozole's use for infertility was illegal worldwide; however, such off-label uses are legal in many countries such as the US and UK.Letrozle(Femara) 2.5mg Benefit
Femara is a powerful Aromatase Inhibitor that was developed to fight breast cancer. For athletes and bodybuilders, it is a drug used to combat the estrogenic side effects of anabolic steroids water-retention, acne and gynocomastia. It will also raise testosterone levels because of the lowered estrogen in the body. Side effects from include a lowered sex drive and continuous use can lead to lowered lipid function and an impaired immune system. Letrozole is an aromatase inhibitor. It works by reducing the total amount of estrogen produced primarily in the body. This helps to starve cancer cells by depriving them of estrogen.Letrozle(Femara) 2.5mg COA
| Tests | Specifications | Results |
| Appearance | White or off-white crystaline powder | White |
| Crystalline powder | ||
| Solubility | Soluble in Chloroform; | Conform |
| Soluble in ethanol when heated | ||
| ldentification | (1)Maximum absorption in wavelength of 240 nm | Conform |
| Minimum absorption in wavelength of 215 nm | Conform | |
| (2)Infrared spectrum should be in accordance the dominant peak of contrast | In accordance with the dominant peak of contrast | |
| Melting points | 182℃-184℃ | 182℃ |
| Related substances | ≤0.5% | 0.30% |
| Single impurity | ≤0.3% | 0.20% |
| Loss on drying | ≤1.0% | 0.80% |
| [Assay]C17H11N5 | ≥98.0% | 99.20% |
| (On anhydrous basis) | ||
| Conclusion | Conforms Specifications of Enterprise Standard. | |
Letrozle(Femara) 2.5mg Effects
Letrozole as an anti-estrogen is extremely beneficial to breast cancer patients. Many forms of breast cancer actively feed off the estrogen hormone. By inhibiting the production of estrogen, which in turn lowers the amount of circulating estrogen in the body, this has the ability to starve the cancer. For years Nolvadex was the preferred form of treatment for this purpose. Nolvadex actively binds to the estrogen receptor, thereby preventing estrogen from binding. However, it does not inhibit or lower production. Nolvadex is still extremely valuable in breast cancer treatment plans, but many physicians, especially in extreme cases have begun to use AI’s first. Once the cancer is in remission, at this stage a SERM like Nolvadex may replace the AI in an effort to protect against the cancer reappearing. Undeniably, AI’s like Letrozole are the most effect means at combating estrogenic related side effects. However, they can also have a negative impact on cholesterol. Alone AI’s do not appear to have a strong, negative effect on cholesterol, but when coupled with an aromatizing steroid like testosterone the adverse cholesterol effect is enhanced. For this reason, many will find SERM’s like Tamoxifen Citrate (Nolvadex) should be their first choice in estrogen protection. SERM’s will not negatively affect cholesterol; in fact, SERM’s, while anti-estrogenic, actively act as estrogens in the liver, and in turn, promote healthier cholesterol levels. We’ll look at this in more detail in the side effect section, and while Letrozole can be used without an adverse cholesterol effect, it will take some effort on your part.Letrozle(Femara) 2.5mg Usage
Letrozole is used treat early breast cancer in women who have experienced menopause and who have had other treatments, such as radiation or surgery to remove the tumor. It is also used to treat early breast cancer in women who have experienced menopause and who have already been treated with a medication called tamoxifen (Nolvadex) for 5 years. Letrozole is also used in women who have experienced menopause as a first treatment of breast cancer that has spread within the breast or to other areas of the body or in women whose breast cancer has worsened while they were taking tamoxifen.
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| ID | Item | Capacity |
| 1 | Clenbuterol | 40mcg*100/bottle |
| 2 | Clomid(Clomiphene) | 50mg*100/bottle |
| 3 | Letrozle(Femara) | 2.5mg*100/bottle |
| 4 | Halotestin(Fluoxymesterone) | 10mg*100/bottle |
| 5 | Dianabol(Methandrostenolone) | 10mg*100/bottle |
| 6 | Dianabol(Methandrostenolone) | 20mg*100/bottle |
| 7 | Dianabol(Methandrostenolone) | 50mg*100/bottle |
| 8 | Proviron(Mesterolone) | 10mg*100/bottle |
| 9 | Proviron(Mesterolone) | 25mg*100/bottle |
| 10 | Primobolan(Methenolone Acetate) | 10mg*100/bottle |
| 11 | Primobolan(Methenolone Acetate) | 25mg*100/bottle |
| 12 | Primobolan(Methenolone Acetate) | 50mg*100/bottle |
| 13 | Superdrol(Methasterone) | 10mg*100/bottle |
| 14 | T3(Liothytonine Sodium) | 25mcg*100/bottle |
| 15 | T3(Liothytonine Sodium) | 40mcg*100/bottle |
| 16 | T4 | 40mcg*100/bottle |
| 17 | Anavar(Oxandrolone) | 10mg*100/bottle |
| 18 | Anavar(Oxandrolone) | 25mg*100/bottle |
| 19 | Anavar(Oxandrolone) | 50mg*100/bottle |
| 20 | Anadrol(Oxymetholone) | 50mg*100/bottle |
| 21 | Winstrol(Stanozolol) | 10mg*100/bottle |
| 22 | Winstrol(Stanozolol) | 20mg*100/bottle |
| 23 | Winstrol(Stanozolol) | 50mg*100/bottle |
| 24 | Turinabol(Chlordehydromethyltestosterone) | 10mg*100/bottle |
| 25 | Turinabol(Chlordehydromethyltestosterone) | 25mg*100/bottle |
| 26 | Nolvadex(Tamoxifen) | 10mg*100/bottle |
| 27 | Nolvadex(Tamoxifen) | 20mg*100/bottle |
| 28 | Aromasin(Exemestane) | 25mg*100/bottle |
| 29 | Arimidex(Anastrozole) | 1mg*100/bottle |
| 30 | Viagra(Sildenafil) | 100mg*100/bottle |
| 31 | Cialis(Tadanafil) | 20mg*100/bottle |
